Renal
Welcome to our last newsletter for 2019 where we focus on Renal Nuclear Medicine.
Radioactive tracers used for Renal imaging: DMSA, DTPA & MAG-3
How the kidneys handle these tracers: DMSA Binds irreversibly to proximal renal tubules & localizes to cortex
DTPA Cleared entirely by glomerular filtration
MAG-3 Cleared almost exclusively by tubular secretion (98%)
Main uses: DMSA For imaging the renal cortex (Fig.1) & provides the most accurate differential renal function
DTPA & MAG-3 For renal perfusion, excretion & clearance (Fig.2). Provides differential function. Renal extraction efficiency is hig
her with MAG-3 and preferred in renal impairment
Other Uses: DTPA or MAG-3 with Frusemide: Evaluate renal outflow tract obstruction (Fig.3)
DTPA or MAG-3 with Captopril: Evaluate renal artery stenosis
About the Author:
Dr June Yap graduated from UNSW with 1st class honours in 1997 Trained at Liverpool & St George Hospitals in Nuclear Medicine & PET Staff Specialist at Liverpool Hospital Nuclear Medicine Physician at NMI for more than 10 years